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PAPPA Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987377
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50-198-7377 100 μL
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Catalog No. 50-198-7377 Supplier Bioss Supplier No. BS6618R
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Rabbit Polyclonal Antibody

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down′s syndrome (trisomy 21).

Specifications

Antigen PAPPA
Applications ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PAPPA
Gene Accession No. Q13219
Gene Alias ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; Insulin-like growth factor-dependent IGF-binding protein 4 protease; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; Pappalysin-1; pregnacy-associated plasma protein A; Pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Gene Symbols PAPPA
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PAPPA.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5069
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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