Invitrogen™ PAPSS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529863

Catalog No. PIPA529863

Description

Recommended positive controls: H1299, HeLa. Predicted reactivity: Mouse (96%), Rat (96%), Xenopus laevis (86%), Rabbit (95%), Rhesus Monkey (98%), Bovine (93%), Guinea pig (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Specifications

• Antigen: PAPSS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAPSS2
• Gene Alias: 1810018P12Rik; 3'-phosphoadenosine 5'-phosphosulfate synthase 2; 3'-phosphoadenosine-5'-phosphosulfate synthase; 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2; adenosine 5'-phosphosulfate kinase; Adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenylylsulfate 3'-phosphotransferase; Adenylyl-sulfate kinase; AI159688; APS kinase; ATP sulfurylase/adenosine 5'-phosphosulfate kinase; ATP sulfurylase/APS kinase 2; ATPSK2; AtpsU2; ATP-sulfurylase; BCYM4; Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2; bm; brachymorphic; PAPS synthase 2; PAPS synthetase 2; PAPS synthethase 2; PAPSS 2; PAPSS2; SAT; SK 2; SK2; Sulfate adenylate transferase; Sulfate adenylyltransferase; sulfurylase kinase 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9060
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O95340
• Gene Symbols: PAPSS2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 236 of Human PAPSS2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG