PAR1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA530590

Catalog No. PIPA530590

Description

Recommended positive controls: Jurkat, HUVEC, unboiled K562. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Thrombin is a serine protease that is involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors which include PAR-1, PAR-2 and PAR3.

Specifications

• Antigen: PAR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F2R
• Gene Alias: AI482343; C HTR; Cf2r; coagulation factor II (thrombin) receptor; coagulation factor II receptor; coagulation factor II thrombin receptor; F2R; HTR; PAR1; PAR-1; protease activated receptor 1; protease-activated receptor 1; proteinase-activated receptor 1; Thrombin receptor; ThrR; TR; TRGPC
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2149
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P25116
• Gene Symbols: F2R
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 90 of Human Thrombin Receptor
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov