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PARK2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984243
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50-198-4243 100 μL
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Catalog No. 50-198-4243 Supplier Bioss Supplier No. BS1865R
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Description

Rabbit Polyclonal Antibody

The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Specifications

Antigen PARK2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PRKN
Gene Accession No. O60260
Gene Alias AAN12155.1; AR-JP; CG10523; CG10523 gene product from transcript CG10523-RB; CG10523-PB; CG10523-PC; Dmel\CG10523; Dmel_CG10523; Dpark; dparkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; Park; PARK2; Parkin; parkin 2; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; PRKN; SD01679
Gene Symbols PRKN
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human E3 ubiquitin-protein ligase parkin.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5071
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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