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  6. Invitrogen™ Parkin Recombinant Rabbit Monoclonal Antibody (21H24L9), HRP, Invitrogen™ 

Invitrogen™ Parkin Recombinant Rabbit Monoclonal Antibody (21H24L9), HRP, Invitrogen™

Catalog No. 702785RHRP2
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50 μg
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Catalog No. Quantity
70-278-5RHRP2 20 μg
70-278-5RHRP 50 μg
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Catalog No. 70-278-5RHRP2 Supplier Invitrogen™ Supplier No. 702785RHRP20UG
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include: better specificity, lot-to-lot consistency, and broader immunoreactivity to diverse targets due to a larger rabbit immune repertoire. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Parkin
Applications Western Blot
Classification Recombinant Monoclonal
Clone 21H24L9
Concentration 1.0 mg/mL
Conjugate HRP
Formulation PBS with proprietary stabilizer and proprietary preservative; pH 7.4
Gene PRKN
Gene Accession No. O60260, Q9JK66, Q9WVS6
Gene Alias AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel\CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679
Gene Symbols PRKN
Host Species Rabbit
Immunogen Protein corresponding to human Parkin (aa1-aa465).
Purification Method Protein A
Quantity 20 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5071, 50873, 56816
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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