Invitrogen™ PARL Monoclonal Antibody (4F4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA522148

Catalog No. PIMA522148

Description

Peptide Sequence: AWRGWAQRGW GCGQAWGASV GGRSCEELTA VLTPPQLLGR RFNFFIQQKC GFRKAPRKVE PRRSDPGTSG EAYKRSALIP PVEETVFYPS PYPIRSLIK.

This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PARL
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9H300
• Gene Symbols: PARL
• Immunogen: PARL (NP_061092.3, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA
• Clone: 4F4
• Conjugate: Unconjugated
• Gene: PARL
• Gene Alias: D16Ertd607e; Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Parl; parl {ECO:0000250; Pbeta; P-beta; presenilin associated rhomboid like; presenilin associated, rhomboid-like; presenilin associated, rhomboid-like isoform 1 preproprotein; presenilin associated, rhomboid-like preproprotein; presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; Psarl; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1; UniProtKB:Q9H300}
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55486
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid