Invitrogen™ PARL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596978

Catalog No. PIPA596978

Description

Immunogen sequence: MAWRGWAQRG WGCGQAWGAS VGGRSCEELT AVLTPPQLLG RRFNFFIQQK CGFRKAPRKV EPRRSDPGTS GEAYKRSALI PPVEETVFYP SPYPIRSLIK PLFFTVGFTG CAFGSAAIWQ YESLKSRVQS YFDGIKADWL DSIRPQKEGD FRKEINKWWN NLSDGQRTVT; Positive Samples: HepG2, MCF7; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein, Nucleus.

This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PARL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PARL
• Gene Alias: D16Ertd607e; Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Parl; parl {ECO:0000250; Pbeta; P-beta; presenilin associated rhomboid like; presenilin associated, rhomboid-like; presenilin associated, rhomboid-like isoform 1 preproprotein; presenilin associated, rhomboid-like preproprotein; presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; Psarl; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1; UniProtKB:Q9H300}
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55486
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9H300
• Gene Symbols: PARL
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human PARL (NP_0010327281).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG