PARN Monoclonal Antibody (OTI2D9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802721

Catalog No. 50-167-9371

Description

The protein encoded by this gene is a 3′-exoribonuclease, with similarity to the RNase D family of 3′-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PARN
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O95453
• Gene Symbols: PARN
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-266 of human PARN produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: OTI2D9
• Conjugate: Unconjugated
• Gene: PARN
• Gene Alias: DAN, DKCB6, PFBMFT4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5073
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid