PARN Mouse anti-Human, Clone: OTI1G7, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-6120	100 μg

Catalog No. 50-166-6120 Supplier OriGene Supplier No. CF802720

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a 3′-exoribonuclease, with similarity to the RNase D family of 3′-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PARN
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1G7
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: PARN
• Gene Accession No.: O95453
• Gene Alias: DAN, DKCB6, PFBMFT4
• Gene Symbols: PARN
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-266 of human PARN produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5073
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b