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  5. Tocris Bioscience™ Paroxetine maleate

Tocris Bioscience™ Paroxetine maleate
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Catalog No. 214150
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Catalog No. Quantity
21-415-0 50 mg
21-411-0R 10 mg
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Catalog No. 21-415-0 Supplier Tocris Bioscience™ Supplier No. 2141/50
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Description

Highly potent and selective 5-HT uptake inhibitor

Paroxetine maleate is a highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for α1-, α2- or β-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo.

Specifications

Quantity 50 mg
Product Type Paroxetine maleate
Purity >99%
Molecular Weight (g/mol) 445.44
Inhibitors Paroxetine maleate

For Research Use Only

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