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PARP1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501560225
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20 μL; Unconjugated
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Catalog No.
50-156-0225 20 μL; Unconjugated
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Catalog No. 50-156-0225 Supplier Bethyl Laboratories, Inc Supplier No. A301376AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

Specifications

Antigen PARP1
Applications Immunofluorescence, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PARP1
Gene Accession No. P09874
Gene Alias PARP
Gene Symbols PARP1
Host Species Rabbit
Immunogen Between 50 and 100
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 142
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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