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Invitrogen™ PARP16 Polyclonal Antibody
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Catalog No. PIPA532130
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100 μL
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PIPA532130 100 μL
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Catalog No. PIPA532130 Supplier Invitrogen™ Supplier No. PA532130
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: PC-3, U87-MG. Predicted reactivity: Mouse (91%), Rat (91%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PARP16
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene PARP16
Gene Accession No. Q8N5Y8
Gene Alias ADP-ribosyltransferase diphtheria toxin-like 15; ARTD15; BC055447; C15orf30; C79952; LRRGT00109; mono [ADP-ribose] polymerase PARP16; PARP16; PARP-16; pART15; poly (ADP-ribose) polymerase family, member 16; poly [ADP-ribose] polymerase 16; poly(ADP-ribose) polymerase family member 16; Protein mono-ADP-ribosyltransferase PARP16; RGD1306243
Gene Symbols PARP16
Host Species Rabbit
Immunogen Recombinant protein fragment corresponding to a region within amino acids 119 and 307 of Human PARP16.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54956
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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