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Tocris Bioscience™ PARPYnD
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Catalog No. 74102
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74-102 2 mg
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Catalog No. 74-102 Supplier Tocris Bioscience™ Supplier No. 7410/2
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Description

PARP inhibitor; photoaffinity probe

PARPYnD is a potent photoaffinity probe for poly(ADP-ribose) polymerase (PARP) (IC50 values for PARP2, PARP1 and PARP6 are 6, 38 and 230 nM, respectively). PARPYnD labels PARP1 and PARP2 in the cell when an N3 functionalized fluorescent probe is attached and can inhibit isolated PARP6.

Specifications

Chemical Name or Material 3-(3-Butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-3 H-diazirine-3-propanamide
CAS 2561483-27-8
Quantity 2 mg
Target Poly(ADP-ribose) Polymerase Inhibitors
Molecular Formula C34H31N9O3
Purity 0.95
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