Invitrogen™ PARVA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA125074

Catalog No. PIPA125074

Description

Recommended positive controls: ECV304. PA1-25074 is expected to cross react with human (94% conserved) and rat (100% conserved) due to sequence homology. The PA1-25074 immunogen is a synthetic peptide gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35-53 of Mouse Parvin alpha. The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin.

The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Specifications

• Antigen: PARVA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PARVA
• Gene Alias: 2010012A22Rik; 5430400F08Rik; Actopaxin; Actp; AI225929; Alpha-parvin; alpha-parvin-like; AU042898; Calponin-like integrin-linked kinase-binding protein; CH-ILKBP; FLJ10793; FLJ12254; I79_014720; Matrix-remodeling-associated protein 2; MNCb-0301; MXRA2; PARVA; Parvin; parvin alpha; parvin, alpha
• Host Species: Rabbit
• Purification Method: IgG fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 55742, 57342
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 8.3 mg/mL
• Formulation: PBS with 15 mM sodium azide; pH 7.4
• Gene Accession No.: Q9EPC1, Q9NVD7
• Gene Symbols: PARVA
• Immunogen: Synthetic peptide gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35-53 of Mouse Parvin alpha. The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov