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Invitrogen™ Parvalbumin Monoclonal Antibody (3C9)

Catalog No. PIMA547312
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500 μL
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PIMA547312 500 μL
PIMA547410 100 μL
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Catalog No. PIMA547312 Supplier Invitrogen™ Supplier No. MA547312
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Description

Mouse Monoclonal Antibody

Parvalbumin Monoclonal Antibody for Western Blot, IHC (PFA), ICC/IF

Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Parvalbumin
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3C9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene Pvalb
Gene Accession No. P02625, P20472, P32848, Q0VCG3
Gene Alias D22S749; HGNC:9704; MGC116759; PALB1; Parv; parvalbumin; Parvalbumin (calcium binding protein); parvalbumin alpha; PV; Pva; PVALB
Gene Symbols Pvalb
Host Species Mouse
Immunogen Full-length recombinant human protein expressed in and purified from E. coli.
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100069554, 100157265, 19293, 25269, 538603, 5816
Target Species Human, Mouse, Rat, Bovine, Pig, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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