Invitrogen™ PAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590700

Catalog No. PIPA590700

Description

Immunogen sequence: LEEIAIDCHN KETEQRLLQE AHDLHLSSLQ LAKKAFGEFN VQTAKHYGNL GRLYQSMRKF KEAEEMHIKA IQIKEQLLGQ EDYEVALSVG HLASLYNYDM NQYENAEKLY LRSIAIGKKL FGEGYSGLEY DYRGLIKLYN SIGNYEKVFE YHNVLSNWNR LRDRQYSVTD ALEDVSTSPQ STEEVVQSFL ISQNVEGPSC; Positive Samples: A-431, HeLa, Jurkat, Raji, Mouse kidney, Mouse brain, Rat kidney, Rat brain; Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, cytoskeleton.

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.

Specifications

• Antigen: PAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APPBP2
• Gene Alias: 1300003O07Rik; AI465480; amyloid beta precursor protein (cytoplasmic tail) binding protein 2; amyloid beta precursor protein binding protein 2; amyloid beta precursor protein-binding protein 2; Amyloid protein-binding protein 2; Appbp2; APP-BP2; appbp2 {ECO:0000312; EMBL:ABQ00241.1}; HS.84084; KIAA0228; PAT1; Protein interacting with APP tail 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10513, 303396, 66884
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.7 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: A5HK05, Q92624, Q9DAX9
• Gene Symbols: APPBP2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 386-585 of human APPBP2 (NP_0063712).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov