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Invitrogen™ PATE3 Polyclonal Antibody
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Catalog No. PIPA596096
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PIPA596096 100 μL
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Catalog No. PIPA596096 Supplier Invitrogen™ Supplier No. PA596096
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MNKHFLFLFL LYCLIVAVTS LQCITCHLRT RTDRCRRGFG VCTAQKGEAC MLLRIYQRNT LQISYMVCQK FCRDMTFDLR NRTYVHTCCN YNYCNFKL; Positive Samples: HeLa.

PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein that contains one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein that is expressed in prostate and testis. The gene that encodes PATE3 consists of around 3,490 bases and maps to human chromosome 11p15.5. Chromosome 11, which comprises approximately 4% of the human genome, is considered a gene and disease association-dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PATE3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PATE3
Gene Accession No. B3GLJ2
Gene Alias Acrosomal vesicle protein HEL-127; epididymis-specific ESC112; Gm17365; HEL-127; Pate3; PATE-DJ; PATE-like protein DJ; predicted gene, 17365; prostate and testis expressed 3; prostate and testis expressed DJ; prostate and testis expressed protein 3; secreted TFP/Ly-6/uPAR protein PATE-DJ
Gene Symbols PATE3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human PATE3 (NP_0011233553).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100169851
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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