Invitrogen™ PAX5 Recombinant Rabbit Monoclonal Antibody (4I0X4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542928

Catalog No. PIMA542928

Description

Positive test controls include: Raji. Immunogen sequence: DEGIQESPVP NGHSLPGRDF LRKQMRGDLF TQQQLEVLDR VFERQHYSDI FTTTEPIKPE QTTEYSAMAS LAGGLDDMKA NLASPTPADI GSSVPGPQSY P.

PAX5 is a member of the paired box (PAX) family of transcription factors. The PAX proteins are important regulators in early development and alterations in the expression of their genes are thought to contribute to neoplastic transformation. PAX5 is the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages, of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis. Mutations in the gene can result in leukemia, acute lymphoblastic 3.

Specifications

• Antigen: PAX5
• Classification: Recombinant Monoclonal
• Concentration: 0.38 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q02548, Q02650
• Gene Symbols: PAX5
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PAX5 (Q02548).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 4I0X4
• Conjugate: Unconjugated
• Gene: PAX5
• Gene Alias: ALL3; B-cell lineage specific activator; B-cell-specific transcription factor; BSAP; EBB-1; KLP; paired box 5; paired box gene 5; paired box gene 5 (B-cell lineage specific activator); paired box homeotic gene 5; paired box protein Pax-5; paired domain gene 5; Pax5; Pax-5; Pax5 variant 1; Pax5 variant 2; RGD1565236; transcription factor PAX 5
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18507, 5079
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid