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Description
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | PAX6 |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | SPM612 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant human PAX6. |
| Dilution | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS (0.05% BSA, 0.05% sodium azide). |
| Gene Alias | AN/AN2/D11S812E/MGC17209/MGDA/WAGR |
| Gene Symbols | PAX6 |
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