Pax7 Antibody (SPM613), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247923AF350

Catalog No. NP247923A30

Description

Pax7 Monoclonal specifically detects Pax7 in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Pax7
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: PAX7
• Immunogen: Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
• Content And Storage: Store at 4°C in the dark.

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: SPM613
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers
• Gene ID (Entrez): 5081.0
• Target Species: Human, Mouse
• Isotype: IgG1 κ