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Invitrogen™ PAX7 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA1117
Description
Western blot analysis of PA1-117 detects a prominent ~54 kDa protein in human HeLa, MCF7, rhabdomyosarcoma and skeletal muscle satellite cells and a weaker ~57 kDa protein in HeLa, rhabdomyosarcoma and skeletal muscle satellite cells. The ~57 kDa band seems to be enriched in immunoprecipitations from HeLa lysate, suggesting a bias for the larger isoform in ths application. Weak unknown bands of lower molecular weight and at ~110-130 kDa are also detected. Specificity of the antibody was also confirmed in Hela cells overexpressing full length PAX7.
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
Specifications
PAX7 | |
Polyclonal | |
Unconjugated | |
PAX7 | |
FLJ37460; HUP1; paired box 7; paired box gene 7; paired box homeotic gene 7; paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7; Pax-7; PAX7 transcriptional factor; PAX7A; PAX7B; RGD1564360; RMS2 | |
Rabbit | |
Protein G | |
RUO | |
18509, 5081 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide | |
P23759, P47239 | |
PAX7 | |
Purified internal fragment of human recombinant PAX7 expressed in E. coli. | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
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