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Invitrogen™ PAX8 Monoclonal Antibody (1F8-3A8)
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Catalog No. PIMA1117
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100 μg
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Catalog No. Quantity
PIMA1117 100 μg
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Catalog No. PIMA1117 Supplier Invitrogen™ Supplier No. MA1117
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Description

Mouse Monoclonal Antibody

Western blot analysis of MA1-117 detects a prominent ~48 kDa protein in human adenocarcinoma SKOV-3 and SV40 transformed African green monkey (Cercopithecus aethiops) kidney cells. In SKOV-3 cells, additional unknown low molecular bands are also detected. Specificity of the antibody was confirmed in HeLa (negative control) and 293T cells overexpressing full length PAX8.

This gene encodes a member of the paired box family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAX8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1F8-3A8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene PAX8
Gene Accession No. Q00288, Q06710
Gene Alias HGNC:8622; paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8; PAX8; Pax-8; Pax-8 protein
Gene Symbols PAX8
Host Species Mouse
Immunogen Purified internal fragment of human recombinant PAX8 expressed in E. coli.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18510, 7849
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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