Invitrogen™ PAX8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521368

Catalog No. PIPA521368

Description

Recommended positive controls: 293T, 293T nuclear extract, DDDDK-tagged PAX8-transfected 293T. Predicted reactivity: Mouse (98%), Rat (99%), Xenopus laevis (91%), Dog (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the paired box family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: PAX8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAX8
• Gene Alias: HGNC:8622; paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8; PAX8; Pax-8; Pax-8 protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18510, 7849, 81819
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.84 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P51974, Q00288, Q06710
• Gene Symbols: PAX8
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 204 (Q06710) of PAX8C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov