Invitrogen™ Paxillin Chimeric Recombinant Rabbit Monoclonal Antibody (LD4 sAB)

Catalog No.	Quantity
PIMA547942	200 μg

Catalog No. PIMA547942

Supplier: Invitrogen™ MA547942

Description

Rabbit Recombinant Monoclonal Antibody

Specificity: The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: Paxillin Chimeric
• Applications: ELISA, Western Blot
• Classification: Recombinant Monoclonal
• Clone: LD4 sAB
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% ProClin 300
• Gene: PXN
• Gene Accession No.: P49023
• Gene Alias: adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
• Gene Symbols: PXN
• Host Species: Rabbit
• Immunogen: Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP; peptide sequence: WGGSATRELDELMASLSD.
• Purification Method: Protein A
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5829
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG κ