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Invitrogen™ Paxillin Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5111334
Description
Immunogen sequence: ALNGTILDPL DQWQPSGSRF IHQQPQSSSP VYGSSAKTSS VSNPQDSVGS PCSRVGEEEH VYSFPNKQKS AEPSPTVMST SL.
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Specifications
Paxillin | |
Polyclonal | |
Unconjugated | |
PXN | |
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
5829 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot, Immunocytochemistry | |
0.10 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P49023 | |
PXN | |
Recombinant Protein corresonding to Human Paxillin. Recombinant protein control fragment (Product #a href=. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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