Tocris Bioscience™ PB 28 dihydrochloride
High affinity σ2 agonist
Supplier: Tocris Bioscience™ 2562/10
DescriptionPB 28 dihydrochloride is a high affinity σ2 receptor agonist (Ki values are 0.8 and 15.2 nM for σ2 and σ1 receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC50 values are 2.62 and 3.96 μM respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.
|Soluble to 20mM with gentle warming in water|
|Observed MW: 443.5|
Safety and Handling
Recommended Storage : Desiccate at +4°C
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only