PBX1 Monoclonal Antibody (OTI1H5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502941

Catalog No. 50-167-3937

Description

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, tinvolving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PBX1
• Classification: Monoclonal
• Concentration: 0.6 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P40424
• Gene Symbols: PBX1
• Immunogen: Full length human recombit protein of human PBX1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1H5
• Conjugate: Unconjugated
• Gene: PBX1
• Gene Alias: CAKUHED
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5087
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid