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Invitrogen™ PBX1 Polyclonal Antibody
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Catalog No. PIPA519312
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100 μg
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PIPA519312 100 μg
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Catalog No. PIPA519312 Supplier Invitrogen™ Supplier No. PA519312
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Goat Polyclonal Antibody

This antibody is predicted to react with canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PBX1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene PBX1
Gene Accession No. P40424, P41778
Gene Alias 2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1; PRL
Gene Symbols PBX1
Host Species Goat
Immunogen Synthetic peptide sequence (ATNVSAHGSQANSPS) corresponding to the internal amino acids of PBX1 (aa 313-327).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18514, 304947, 5087
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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