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Invitrogen™ PBX1 Polyclonal Antibody
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Catalog No. PIPA582100
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100 μL
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PIPA582100 100 μL
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Catalog No. PIPA582100 Supplier Invitrogen™ Supplier No. PA582100
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PRLMHSHAGV GMAGHPGLSQ HLQDGAGGTE GEGGRKQDIG DILQQIMTIT DQSLDEAQAR KHALNCHRMK PALFNVLCEI KEKTVLSIRG AQEEEPTDPQ LMRLDNMLLA EGV Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 77%.

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PBX1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PBX1
Gene Accession No. P40424, P41778
Gene Alias 2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1; PRL
Gene Symbols PBX1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PBX1. Recombinant protein control fragment (Product #RP-101910).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18514, 304947, 5087
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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