PBX1b Monoclonal Antibody (CT 41.1), Active Motif™
Mouse Monoclonal Antibody
Supplier: Active Motif 61165
DescriptionThis gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
|PBS with 30% glycerol and 0.035% sodium azide; pH 7.5|
|This PBX1b antibody was raised against a recombinant protein corresponding to amino acids 319 - 347 of human PBX1b.|
|ChIP Assay, Immunohistochemistry, Western Blot|
|2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; Homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; Pre-B-cell leukemia transcription factor 1; PRL|
|-20°C, Avoid Freeze/Thaw Cycles|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok