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Pc2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572504
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50-157-2504 10 μL
50-157-2503 100 μL
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Catalog No. 50-157-2504 Supplier Bethyl Laboratories, Inc Supplier No. IHC00668T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Rabbit, Guinea pig_10141, Pig, Panda, Monkey, Gorilla, Chimpanzee, Gray short

CBX4 is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintece of proper expression patterns of developmental master regulators; changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system responsible for the inheritance of gene activity by progeny cells. It participates in maintaining the transcriptionally repressive state of genes. CBX4 is part of acomplex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ′Lys-119′, rendering chromatin heritably changed in its expressibility. CBX4 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I.

Specifications

Antigen Pc2
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CBX4
Gene Accession No. O00257, O55187
Gene Alias E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; Pc2; hPc2
Gene Symbols Cbx4
Host Species Rabbit
Immunogen Between 150 and 200
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12418, 8535
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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