PCBP1 Mouse anti-Human, Clone: OTI10B7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF806327

Catalog No. 50-166-7793

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5′-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

Specifications

• Antigen: PCBP1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PCBP1
• Gene Alias: HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5093
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI10B7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q15365
• Gene Symbols: PCBP1
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-225 of human PCBP1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1