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PCBP1 Mouse anti-Human, Clone: OTI10B7, lyophilized, TrueMAB™
SDP

Catalog No. 501667793
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100 μg
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50-166-7793 100 μg
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Catalog No. 50-166-7793 Supplier OriGene Supplier No. CF806327
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5′-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

Specifications

Antigen PCBP1
Applications Western Blot
Classification Monoclonal
Clone OTI10B7
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene PCBP1
Gene Accession No. Q15365
Gene Alias HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
Gene Symbols PCBP1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-225 of human PCBP1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5093
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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