Invitrogen™ PCBP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520359

Catalog No. PIPA520359

Description

A suggested positive control is Hela cell lysate. PA5-20359 can be used with blocking peptide PEP-0479.

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

Specifications

• Antigen: PCBP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCBP4
• Gene Alias: 1200003L19Rik; alpha CP-4; alpha-CP4; AlphaCP-4; alphaCP-4 protein; CBP; LIP4; LYST-interacting protein; MCG10; Pcbp4; poly(rC) binding protein 4; poly(rC)-binding protein 4; RNA binding protein MCG10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57060
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P57723
• Gene Symbols: PCBP4
• Immunogen: A 17 amino acid peptide from near the carboxy terminus of human MCG10.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov