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Invitrogen™ PCCA Monoclonal Antibody (OTI1E9)
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Catalog No. PIMA527386
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100 μL
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PIMA527386 100 μL
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Catalog No. PIMA527386 Supplier Invitrogen™ Supplier No. MA527386
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Mouse Monoclonal Antibody

PCCA Monoclonal Antibody for Western Blot, IHC (P)

This protein is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine. It is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. The protein is located in the mitochondrial matrix. Defects in PCCA are the cause o propionic acidemia type I (PA-1). PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, develop-mental retardation, and intolerance to protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCCA
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1E9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PCCA
Gene Accession No. P05165
Gene Alias C79630; Pcca; pccA complementation group; PCCase alpha subunit; PCCase subunit alpha; propanoyl-CoA:carbon dioxide ligase alpha subunit; propanoyl-CoA:carbon dioxide ligase subunit alpha; propionyl CoA carboxylase, alpha polypeptide; propionyl CoA-carboxylase alpha; Propionyl Coenzyme A carboxylase alpha polypeptide; propionyl Coenzyme A carboxylase, alpha polypeptide; propionyl-CoA carboxylase alpha chain, mitochondrial; propionyl-CoA carboxylase alpha subunit; propionyl-Coenzyme A carboxylase, alpha polypeptide; RP11-151A6.1
Gene Symbols PCCA
Host Species Mouse
Immunogen Full length human recombinant protein of PCCA produced in HEK293T cell.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5095
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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