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Invitrogen™ PCDH12 Polyclonal Antibody
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Catalog No. PIPA520703
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100 μg
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Catalog No. Quantity
PIPA520703 100 μg
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Catalog No. PIPA520703 Supplier Invitrogen™ Supplier No. PA520703
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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20703 can be used with blocking peptide PEP-0818.

Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDH12
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PCDH12
Gene Accession No. O55134, Q9NPG4
Gene Alias Pcdh12; Pcdh14; protocadherin 12; protocadherin 14; protocadherin-12; Protocadherin-12, secreted form; UNQ395/PRO731; Vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2; VECAD2; VE-cad-2; VE-cadherin 2; VE-cadherin-2
Gene Symbols PCDH12
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of human PCDH12.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116808, 51294, 53601
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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