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Invitrogen™ PCDH15 Polyclonal Antibody
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Catalog No. PIPA547865
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100 μg
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PIPA547865 100 μg
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Catalog No. PIPA547865 Supplier Invitrogen™ Supplier No. PA547865
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Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Protocadherin-1, rhProtocadherin-8, and rhProtocadherin-10 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDH15
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene PCDH15
Gene Accession No. Q96QU1
Gene Alias Ames waltzer; av; BB078305; cadherin-related family member 15; CDHR15; DFNB23; DKFZp667A1711; ENSMUSG00000046980; Gm9815; nmf19; Pcdh15; protocadherin 15; protocadherin 15 CD2; protocadherin 15 CD3 isoform; protocadherin related 15; protocadherin-15; protocadherin-15-CD2; protocadherin-related 15; RP11-449J3.2; USH1F
Gene Symbols PCDH15
Host Species Sheep
Immunogen CHO-derived recombinant human Protocadherin-15 Gln27-Ala1376.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65217
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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