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Invitrogen™ PCDH15 Polyclonal Antibody
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Catalog No. PIPA5116505
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100 μL
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PIPA5116505 100 μL
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Catalog No. PIPA5116505 Supplier Invitrogen™ Supplier No. PA5116505
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Description

Rabbit Polyclonal Antibody

Positive Samples: SH-SY5Y, 293T, A-549, Raji, Mouse brain, Mouse liver, Mouse spleen, Rat brain, Rat liver Immunogen sequence: TVNELTPVGT TIFTGFSGDN GATDIDDGPN GQIEYVIQYN PDDPTSNDTF EIPLMLTGNI VLRKRLNYED KTRYFVIIQA NDRAQNLNER RTTTTTLTVD VLDGDDLGPM FLPCVLVPNT RDCRPLTYQA AIPELRTPEE LNPIIVTPPI QAIDQDRNIQ PPSDRPGILY SILVGTPEDY PRFFHMHPRT AELSLLEPVN RDFHQKFDLV IKAEQDNGHP LPAFAGLHIE ILDENNQSPY F.

PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDH15
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PCDH15
Gene Accession No. Q96QU1, Q99PJ1
Gene Alias Ames waltzer; av; BB078305; cadherin-related family member 15; CDHR15; DFNB23; DKFZp667A1711; ENSMUSG00000046980; Gm9815; nmf19; Pcdh15; protocadherin 15; protocadherin 15 CD2; protocadherin 15 CD3 isoform; protocadherin related 15; protocadherin-15; protocadherin-15-CD2; protocadherin-related 15; RP11-449J3.2; USH1F
Gene Symbols PCDH15
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_0011362351).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11994, 65217, 690865
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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