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Invitrogen™ PCDH18 Polyclonal Antibody
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Catalog No. PIPA543351
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100 μL
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PIPA543351 100 μL
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Catalog No. PIPA543351 Supplier Invitrogen™ Supplier No. PA543351
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Description

Rabbit Polyclonal Antibody

Peptide sequence: MHQMNAKMHF RFVFALLIVS FNHDVLGKNL KYRIYEEQRV GSVIARLSED Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%.

Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs. Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea. PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development. PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDH18
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PCDH18
Gene Accession No. Q9HCL0
Gene Alias 3110038E07Rik; BB095589; DKFZP434B0923; Kiaa1562; PCDH18; PCDH68L; Protocadherin 18; protocadherin 68-like protein; protocadherin-18
Gene Symbols PCDH18
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human PCDH18 (aa 1-50).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54510
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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