Invitrogen™ PCDHA1 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547694

Catalog No. PIPA547694

Description

Reconstitute at 0.2 mg/mL in sterile PBS.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Specifications

• Antigen: PCDHA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDHA1
• Gene Alias: KIAA0345-like 13; PCDHA1; PCDH-ALPHA1; PCDH-alpha-1; protocadherin alpha 1; protocadherin alpha-1; RPF1
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56147
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9Y5I3
• Gene Symbols: PCDHA1
• Immunogen: Sf 21-derived recombinant human Protocadherin alpha 1 Gln30-Pro689.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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