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Invitrogen™ PCDHA10 Polyclonal Antibody
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Catalog No. PIPA543335
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PIPA543335 100 μL
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Catalog No. PIPA543335 Supplier Invitrogen™ Supplier No. PA543335
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Description

Rabbit Polyclonal Antibody

Peptide sequence: ESRLLDSRFP LEGASDADVG ENALLTYKLS PNEYFVLDII NKKDKDKFPV Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHA10
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PCDHA10
Gene Accession No. Q9Y5I2
Gene Alias cadherin-related neuronal receptor 10; cadherin-related neuronal receptor 3; Cnr3; CNR8; CNRN8; CNRS8; Crnr3; CRNR8; KIAA0345-like 4; ortholog to mouse CNR8; Pcdha10; Pcdha14; PCDH-ALPHA10; PCDH-alpha-10; protocadherin alpha 10; protocadherin alpha 14; protocadherin alpha-10; rCNRv10
Gene Symbols PCDHA10
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human PCDHA10 (aa 143-192).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56139
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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