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Invitrogen™ PCDHA10 Polyclonal Antibody
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Catalog No. PIPA531126
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PIPA531126 100 μL
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Catalog No. PIPA531126 Supplier Invitrogen™ Supplier No. PA531126
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH. Predicted reactivity: Rat (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHA10
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene PCDHA10
Gene Accession No. Q9Y5I2
Gene Alias cadherin-related neuronal receptor 10; cadherin-related neuronal receptor 3; Cnr3; CNR8; CNRN8; CNRS8; Crnr3; CRNR8; KIAA0345-like 4; ortholog to mouse CNR8; Pcdha10; Pcdha14; PCDH-ALPHA10; PCDH-alpha-10; protocadherin alpha 10; protocadherin alpha 14; protocadherin alpha-10; rCNRv10
Gene Symbols PCDHA10
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human PCDHA10. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56139
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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