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Invitrogen™ PCDHA12 Monoclonal Antibody (1D3)
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Catalog No. PIMA522259
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100 μg
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Catalog No. Quantity
PIMA522259 100 μg
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Catalog No. PIMA522259 Supplier Invitrogen™ Supplier No. MA522259
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Description

Mouse Monoclonal Antibody

Peptide Sequence: LTGSVQIQIT VLDVNDNGPA FDKPSYKVVL SENVQNDTRV IQLNASDPDE GLNGEISYGI KMILPVSEKC MFSINPDTGE IRIYGELDFE ENNAYEIQVN AIDKGI.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHA12
Applications ELISA
Classification Monoclonal
Clone 1D3
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene PCDHA12
Gene Accession No. Q9UN75
Gene Alias cadherin-related neuronal receptor 5; Cnr5; Crnr5; KIAA0345-like 2; MGC138485; MGC141932; PCDHA12; Pcdha13; PCDH-ALPHA12; PCDH-alpha-12; protocadherin alpha 12; protocadherin alpha 13; protocadherin alpha-12; rCNRv12
Gene Symbols PCDHA12
Host Species Mouse
Immunogen PCDHA12 (NP_061726, 222 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56137
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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