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Invitrogen™ PCDHA12 Polyclonal Antibody
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Catalog No. PIPA583290
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100 μL
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PIPA583290 100 μL
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Catalog No. PIPA583290 Supplier Invitrogen™ Supplier No. PA583290
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LNGEISYGIK MILPVSEKCM FSINPDTGEI RIYGELDFEE NNAYEIQVNA IDKGIPSMAG HSMVLVEV Highest antigen sequence indentity to the following orthologs: Mouse - 49%, Rat - 50%.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHA12
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PCDHA12
Gene Accession No. Q9UN75
Gene Alias cadherin-related neuronal receptor 5; Cnr5; Crnr5; KIAA0345-like 2; MGC138485; MGC141932; PCDHA12; Pcdha13; PCDH-ALPHA12; PCDH-alpha-12; protocadherin alpha 12; protocadherin alpha 13; protocadherin alpha-12; rCNRv12
Gene Symbols PCDHA12
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PCDHA12. Recombinant protein control fragment (Product #RP-103949).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56137
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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