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Invitrogen™ PCDHA12 Polyclonal Antibody
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Catalog No. PIPA597090
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100 μL
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PIPA597090 100 μL
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Catalog No. PIPA597090 Supplier Invitrogen™ Supplier No. PA597090
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LTLLLYTALR CSAPPTVSRC APGKPTLVCS SAVGSWSYSQ QRRQRVCSAE SPPKTDLMAF SPSLQLSRED CLNPPSEVSY; Positive Samples: HL-60, H460, NIH/3T3, Mouse spinal cord, Mouse brain, Mouse lung, Rat spinal cord, Rat brain; Cellular Location: Cell membrane, Single-pass type I membrane protein.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHA12
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.69 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PCDHA12
Gene Accession No. Q9UN75
Gene Alias cadherin-related neuronal receptor 5; Cnr5; Crnr5; KIAA0345-like 2; MGC138485; MGC141932; PCDHA12; Pcdha13; PCDH-ALPHA12; PCDH-alpha-12; protocadherin alpha 12; protocadherin alpha 13; protocadherin alpha-12; rCNRv12
Gene Symbols PCDHA12
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 713-792 of human PCDHA12 (NP_1140701).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116779, 192164, 56137
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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