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PCDHA2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501726045 Shop All Proteintech Group Inc Products
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50-172-6045 150 μL
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Catalog No. 50-172-6045 Supplier Proteintech Group Inc Supplier No. 101272AP150UL
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Rabbit Polyclonal Antibody

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Specifications

Antigen PCDHA2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene PCDHA2
Gene Accession No. Q9Y5H9
Gene Alias PCDH alpha 2, PCDH ALPHA2, PCDHA2, protocadherin alpha 2
Gene Symbols PCDHA2
Host Species Rabbit
Immunogen PCDHA2 Fusion Protein Ag0173
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56146
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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