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Invitrogen™ PCDHA8 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121449

Catalog No. PIPA5121449


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Description

Description

Antibody tested in Indirect ELISA.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PCDHA8
Polyclonal
Unconjugated
PCDHA8
KIAA0345-like 6; PCDHA8; PCDH-ALPHA8; PCDH-alpha-8; protocadherin alpha 8; protocadherin alpha-8
Rabbit
Protein G
RUO
56140
-20°C or -80°C if preferred
Liquid
ELISA, Immunohistochemistry (Paraffin)
3 mg/mL
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Q9Y5H6
PCDHA8
Recombinant Human Protocadherin alpha-8 protein (719-922aa).
100 μL
Primary
Human
Antibody
IgG
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