Invitrogen™ PCDHB16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531123

Catalog No. PIPA531123

Description

Recommended positive controls: NT2D, IMR32, U87-MG. Predicted reactivity: Chimpanzee (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Specifications

• Antigen: PCDHB16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDHB16
• Gene Alias: cadherin ME1; KIAA1621; ME1; PCDH3X; PCDHB16; PCDHB8a; PCDHbeta 16; PCDH-BETA16; PCDH-beta-16; protocadherin beta 16; protocadherin beta 8a; protocadherin beta-16; Protocadherin-3X
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57717
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9NRJ7
• Gene Symbols: PCDHB16
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 286 of Human PCDHB16.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov