Invitrogen™ PCDHB16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550282

Catalog No. PA550282

Description

The antibody detects endogenous levels of total PCDHB16 protein.

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Specifications

• Antigen: PCDHB16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PCDHB16
• Gene Alias: cadherin ME1; KIAA1621; ME1; PCDH3X; PCDHB16; PCDHB8a; PCDHbeta 16; PCDH-BETA16; PCDH-beta-16; protocadherin beta 16; protocadherin beta 8a; protocadherin beta-16; Protocadherin-3X
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57717
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9NRJ7
• Gene Symbols: PCDHB16
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human protocadherin beta 16.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG