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Invitrogen™ PCDHGA10 Monoclonal Antibody (3A7)
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Catalog No. PIMA522247
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100 μg
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Catalog No. Quantity
PIMA522247 100 μg
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Catalog No. PIMA522247 Supplier Invitrogen™ Supplier No. MA522247
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Description

Mouse Monoclonal Antibody

Peptide Sequence: SDGGDPLRSG TVLVSVTVFD ANDNAPVFTL PEYRVSVPEN LPVGTQLLTV TATDRDEGAN GEVTYSFRKL PDTQLLKFQL NKYTGEIKIS ENLDYEET.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHGA10
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3A7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene PCDHGA10
Gene Accession No. Q9Y5H3
Gene Alias PCDHGA10; PCDH-gamma-A10; protocadherin gamma subfamily A, 10; protocadherin gamma-A10
Gene Symbols PCDHGA10
Host Species Mouse
Immunogen PCDHGA10 (NP_061736.1, 219 a.a. ~ 316 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56106
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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