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Invitrogen™ PCDHGA8 Monoclonal Antibody (1C11)
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Catalog No. PIMA520814
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100 μg
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Catalog No. Quantity
PIMA520814 100 μg
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Catalog No. PIMA520814 Supplier Invitrogen™ Supplier No. MA520814
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Description

Mouse Monoclonal Antibody

Peptide Sequence: LENSLPGTVI AFLSVHDQDS GKNGQVVCYT RDNLPFKLEK SIGNYYRLVT RKYLDRENVS IYNITVMASD LGTPPLSTET QIALHVAD.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCDHGA8
Applications ELISA, Western Blot
Classification Monoclonal
Clone 1C11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene PCDHGA8
Gene Accession No. Q9Y5G5
Gene Alias KIAA0327; PCDHGA8; PCDH-gamma-A8; protocadherin gamma subfamily A, 8; protocadherin gamma-A8
Gene Symbols PCDHGA8
Host Species Mouse
Immunogen PCDHGA8 (NP_114477, 357 a.a. ~ 444 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9708
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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